DNase I Inhibits a Late Phase of Reactive Oxygen Species Production in Neutrophils

Neutrophils kill bacteria on extracellular complexes of DNA fibers and bactericidal proteins known as neutrophil extracellular traps (NETs). The NET composition and the bactericidal mechanisms they use are not fully understood. Here, we show that treatment with deoxyribonuclease (DNase I) impairs a...

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Hauptverfasser: Munafo, Daniela B., Johnson, Jennifer L., Brzezinska, Agnieszka A., Ellis, Beverly A., Wood, Malcolm R., Catz, Sergio D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919508/
https://ncbi.nlm.nih.gov/pubmed/20375609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000235860
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