A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators

BACKGROUND: Mitochondria are highly dynamic organelles whose morphology and position within the cell is tightly coupled to metabolic function. There is a limited list of essential proteins that regulate mitochondrial morphology and the mechanisms that govern mitochondrial dynamics are poorly underst...

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Bibliographische Detailangaben
Hauptverfasser: Schauss, Astrid C, Huang, Huiyan, Choi, Seok-Yong, Xu, Liqun, Soubeyrand, Sébastien, Bilodeau, Patricia, Zunino, Rodolfo, Rippstein, Peter, Frohman, Michael A, McBride, Heidi M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919466/
https://ncbi.nlm.nih.gov/pubmed/20659315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-100
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