TLR4 Asp299Gly and Thr399Ile Polymorphisms: No Impact on Human Immune Responsiveness to LPS or Respiratory Syncytial Virus

BACKGROUND: A broad variety of natural environmental stimuli, genotypic influences and timing all contribute to expression of protective versus maladaptive immune responses and the resulting clinical outcomes in humans. The role of commonly co-segregating Toll-like receptor 4 (TLR4) non-synonymous s...

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Main Authors: Douville, Renée N., Lissitsyn, Yuriy, Hirschfeld, Aaron F., Becker, Allan B., Kozyrskyj, Anita L., Liem, Joel, Bastien, Nathalie, Li, Yan, Victor, Rachel E., Sekhon, Mehtab, Turvey, Stuart E., HayGlass, Kent T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919413/
https://ncbi.nlm.nih.gov/pubmed/20711470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012087
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