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Ketogenic Essential Amino Acids Modulate Lipid Synthetic Pathways and Prevent Hepatic Steatosis in Mice

BACKGROUND: Although dietary ketogenic essential amino acid (KAA) content modifies accumulation of hepatic lipids, the molecular interactions between KAAs and lipid metabolism are yet to be fully elucidated. METHODOLOGY/PRINCIPAL FINDINGS: We designed a diet with a high ratio (E/N) of essential amin...

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Detalhes bibliográficos
Main Authors: Noguchi, Yasushi, Nishikata, Natsumi, Shikata, Nahoko, Kimura, Yoshiko, Aleman, Jose O., Young, Jamey D., Koyama, Naoto, Kelleher, Joanne K., Takahashi, Michio, Stephanopoulos, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919399/
https://ncbi.nlm.nih.gov/pubmed/20706589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012057
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