Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitis

The membrane-bound mucins, MUC17 (human) and Muc3 (mouse), are highly expressed on the apical surface of intestinal epithelia and are thought to be cytoprotective. The extracellular regions of these mucins contain EGF-like Cys-rich segments (CRD1 and CRD2) connected by an intervening linker domain (...

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Main Authors: Luu, Ying, Junker, Wade, Rachagani, Satyanarayana, Das, Srustidhar, Batra, Surinder K., Heinrikson, Robert L., Shekels, Laurie L., Ho, Samuel B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919344/
https://ncbi.nlm.nih.gov/pubmed/20211273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2010.03.001
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