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Synthesis of the fluorescent amino acid rac-(7-hydroxycoumarin-4-yl)ethylglycine
The hydrochloride of the racemic amino acid (7-hydroxycoumarin-4-yl)ethylglycine, a versatile fluorescent probe in proteins, has been synthesized in five steps from commercially available (7-hydroxycoumarin-4-yl)acetic acid. The key step involves the alkylation of a glycine–enolate equivalent.
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Beilstein-Institut
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919258/ https://ncbi.nlm.nih.gov/pubmed/20703371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.6.69 |
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