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Systematic Analysis of Essential Genes Reveals New Regulators of G protein Signaling
The yeast pheromone pathway consists of a canonical heterotrimeric G protein and MAP kinase cascade. To identify new signaling components we systematically evaluated 870 essential genes using a library of repressible-promoter strains. Quantitative transcription-reporter and MAPK activity assays were...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919228/ https://ncbi.nlm.nih.gov/pubmed/20542006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.05.026 |
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