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Lysophosphatidic Acid Signals through Multiple Receptors in Osteoclasts to Elevate Cytosolic Calcium Concentration, Evoke Retraction, and Promote Cell Survival

Lysophosphatidic acid (LPA) is a bioactive phospholipid whose functions are mediated by multiple G protein-coupled receptors. We have shown that osteoblasts produce LPA, raising the possibility that it mediates intercellular signaling among osteoblasts and osteoclasts. Here we investigated the expre...

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Detalhes bibliográficos
Main Authors: Lapierre, Danielle M., Tanabe, Natsuko, Pereverzev, Alexey, Spencer, Martha, Shugg, Ryan P. P., Dixon, S. Jeffrey, Sims, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919141/
https://ncbi.nlm.nih.gov/pubmed/20551326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109322
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