Identification of Glucose Transporter 4 Knockdown-dependent Transcriptional Activation Element on the Retinol Binding Protein 4 Gene Promoter and Requirement of the 20 S Proteasome Subunit for Transcriptional Activity

Retinol binding protein 4 (RBP4) is the transport protein that carries retinol in blood. RBP4 was described recently as a new adipokine that reduced insulin sensitivity. Mice lacking glucose transporter 4 (GLUT4) in adipocytes have enhanced Rbp4 gene expression; however, the molecular mechanism is u...

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Main Authors: Inoue, Erina, Yamashita, Aoi, Inoue, Hirofumi, Sekiguchi, Mariko, Shiratori, Asuka, Yamamoto, Yuji, Tadokoro, Tadahiro, Ishimi, Yoshiko, Yamauchi, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919119/
https://ncbi.nlm.nih.gov/pubmed/20530491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079152
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