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Characterization of the Membrane-targeting C1 Domain in Pasteurella multocida Toxin

Pasteurella multocida toxin (PMT) is a virulence factor responsible for the pathogenesis of some forms of pasteurellosis. The toxin activates G(q)- and G(12/13)-dependent pathways through the deamidation of a glutamine residue in the α-subunit of heterotrimeric GTPases. We recently reported the crys...

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Autori principali: Kamitani, Shigeki, Kitadokoro, Kengo, Miyazawa, Masayuki, Toshima, Hirono, Fukui, Aya, Abe, Hiroyuki, Miyake, Masami, Horiguchi, Yasuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919110/
https://ncbi.nlm.nih.gov/pubmed/20534589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102285
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