Caveolin-1 Protects against Sepsis by Modulating Inflammatory Response, Alleviating Bacterial Burden, and Suppressing Thymocyte Apoptosis

Sepsis is a leading cause of death, which is characterized by uncontrolled inflammatory response. In this study, we report that caveolin-1, a major component of caveolae, is a critical survival factor of sepsis. We induced sepsis using a well established sepsis animal model, cecal ligation and punct...

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Detalhes bibliográficos
Main Authors: Feng, Hong, Guo, Ling, Song, Zhiqing, Gao, Haiqing, Wang, Dan, Fu, Weisi, Han, Jingyan, Li, Zhenyu, Huang, Bin, Li, Xiang-An
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919077/
https://ncbi.nlm.nih.gov/pubmed/20534584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116897
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