Cooperativity between the Phosphorylation of Thr(95) and Ser(77) of NHERF-1 in the Hormonal Regulation of Renal Phosphate Transport

The phosphorylation of the sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) plays a key role in the regulation of renal phosphate transport by parathyroid hormone (PTH) and dopamine. Ser(77) in the first PDZ domain of NHERF-1 is a downstream target of both hormones. The current experiments ex...

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Detalhes bibliográficos
Main Authors: Weinman, Edward J., Steplock, Deborah, Zhang, Yinghua, Biswas, Rajatsubhra, Bloch, Robert J., Shenolikar, Shirish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919075/
https://ncbi.nlm.nih.gov/pubmed/20571032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132423
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