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Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor–1

Parathyroid hormone (PTH), via activation of PKC and/or protein kinase A, inhibits renal proximal tubular phosphate reabsorption by facilitating the internalization of the major sodium-dependent phosphate transporter, Npt2a. Herein, we explore the hypothesis that the effect of PTH is mediated by pho...

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Bibliografiske detaljer
Main Authors: Weinman, Edward J., Biswas, Rajat S., Peng, Quihong, Shen, Lily, Turner, Christina L., E, Xiaofei, Steplock, Deborah, Shenolikar, Shirish, Cunningham, Rochelle
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045615/
https://ncbi.nlm.nih.gov/pubmed/17975671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32738
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