Replacement of the Replication Factors of Porcine Circovirus (PCV) Type 2 with Those of PCV Type 1 Greatly Enhances Viral Replication In Vitro

Porcine circovirus type 1 (PCV1), originally isolated as a contaminant of PK-15 cells, is nonpathogenic, whereas porcine circovirus type 2 (PCV2) causes an economically important disease in pigs. To determine the factors affecting virus replication, we constructed chimeric viruses by swapping open r...

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Detalhes bibliográficos
Main Authors: Beach, N. M., Juhan, N. M., Cordoba, L., Meng, X. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919042/
https://ncbi.nlm.nih.gov/pubmed/20573809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00522-10
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