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Nucleocytoplasmic Shuttling of Human Cytomegalovirus UL84 Is Essential for Virus Growth

Human cytomegalovirus (HCMV) UL84 is a multifunctional protein that is the proposed initiator for lytic viral DNA synthesis. Recently it was shown that UL84 displays nucleocytoplasmic shuttling. The role of shuttling in lytic DNA replication and virus growth is unknown. We now show that expression o...

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Detalhes bibliográficos
Main Authors: Gao, Yang, Kagele, Dominique, Smallenberg, Kate, Pari, Gregory S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919040/
https://ncbi.nlm.nih.gov/pubmed/20573826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00738-10
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