Phorbol Ester-Induced Human Cytomegalovirus Major Immediate-Early (MIE) Enhancer Activation through PKC-Delta, CREB, and NF-κB Desilences MIE Gene Expression in Quiescently Infected Human Pluripotent NTera2 Cells

The ways in which human cytomegalovirus (HCMV) major immediate-early (MIE) gene expression breaks silence from latency to initiate the viral replicative cycle are poorly understood. A delineation of the signaling cascades that desilence the HCMV MIE genes during viral quiescence in the human pluripo...

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Detalhes bibliográficos
Main Authors: Liu, Xiaoqiu, Yuan, Jinxiang, Wu, Allen W., McGonagill, Patrick W., Galle, Courtney S., Meier, Jeffery L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919020/
https://ncbi.nlm.nih.gov/pubmed/20504934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00416-10
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