Breaking Human Cytomegalovirus Major Immediate-Early Gene Silence by Vasoactive Intestinal Peptide Stimulation of the Protein Kinase A-CREB-TORC2 Signaling Cascade in Human Pluripotent Embryonal NTera2 Cells

The triggering mechanisms underlying reactivation of human cytomegalovirus (HCMV) in latently infected persons are unclear. During latency, HCMV major immediate-early (MIE) gene expression breaks silence to initiate viral reactivation. Using quiescently HCMV-infected human pluripotent embryonal NTer...

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Detalhes bibliográficos
Main Authors: Yuan, Jinxiang, Liu, Xiaoqiu, Wu, Allen W., McGonagill, Patrick W., Keller, Michael J., Galle, Courtney S., Meier, Jeffery L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698552/
https://ncbi.nlm.nih.gov/pubmed/19369332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00061-09
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