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Mutagenesis of Adeno-Associated Virus Type 2 Capsid Protein VP1 Uncovers New Roles for Basic Amino Acids in Trafficking and Cell-Specific Transduction

The N termini of the capsid proteins VP1 and VP2 of adeno-associated virus (AAV) play important roles in subcellular steps of infection and contain motifs that are highly homologous to a phospholipase A(2) (PLA(2)) domain and nuclear localization signals (NLSs). To more clearly understand how virion...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Johnson, Jarrod S., Li, Chengwen, DiPrimio, Nina, Weinberg, Marc S., McCown, Thomas J., Samulski, R. Jude
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918992/
https://ncbi.nlm.nih.gov/pubmed/20573820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00687-10
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