Production of the Chiral Compound (R)-3-Hydroxybutyrate by a Genetically Engineered Methylotrophic Bacterium

In this study, a methylotrophic bacterium, Methylobacterium rhodesianum MB 126, was used for the production of the chiral compound (R)-3-hydroxybutyrate (R-3HB) from methanol. R-3HB is formed during intracellular degradation of the storage polymer (R)-3-polyhydroxybutyrate (PHB). Since the monomer R...

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Bibliographic Details
Main Authors: Hölscher, Tina, Breuer, Uta, Adrian, Lorenz, Harms, Hauke, Maskow, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918973/
https://ncbi.nlm.nih.gov/pubmed/20581197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01065-10
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