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Downregulation of active IKKβ by Ro52-mediated autophagy
Upon activation, NF-κB translocates into the nucleus and initiates many biological events. This NF-κB signaling is mainly induced by the protein kinase IKKβ. Early in this signaling pathway, IKKβ is phosphorylated for activation by several factors, such as pro-inflammatory cytokines and the Tax onco...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918734/ https://ncbi.nlm.nih.gov/pubmed/20627395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.05.004 |
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