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Downregulation of active IKKβ by Ro52-mediated autophagy

Upon activation, NF-κB translocates into the nucleus and initiates many biological events. This NF-κB signaling is mainly induced by the protein kinase IKKβ. Early in this signaling pathway, IKKβ is phosphorylated for activation by several factors, such as pro-inflammatory cytokines and the Tax onco...

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Hlavní autoři: Niida, Motoko, Tanaka, Makoto, Kamitani, Tetsu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918734/
https://ncbi.nlm.nih.gov/pubmed/20627395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.05.004
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