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Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus

Several lines of evidence suggest a dysfunctional glutamate system in major depressive disorder (MDD). Recently, we reported reduced levels of metabotropic glutamate receptor subtype 5 (mGluR5) in postmortem brains in MDD, however the neurobiological mechanisms that induce these abnormalities are un...

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Autors principals: Iyo, Abiye H., Feyissa, Anteneh M., Chandran, Agata, Austin, Mark C., Regunathan, Soundar, Karolewicz, Beata
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918667/
https://ncbi.nlm.nih.gov/pubmed/20600666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.06.023
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