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Using Both Cases and Controls for Testing Hardy-Weinberg Proportions in a Genetic Association Study
OBJECTIVES: Assessment of the Hardy-Weinberg proportion (HWP) in controls has been widely used as a quality control measure in case-control association studies. However, when the disease being studied is common, controls might not represent the general population, which could result in inaccurate HW...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918648/ https://ncbi.nlm.nih.gov/pubmed/20203526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000289597 |
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