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Effects of sequence on repeat expansion during DNA replication
Small DNA repeat tracts are located throughout the human genome. The tracts are unstable, and expansions of certain repeat sequences cause neuromuscular disease. DNA expansions appear to be associated with lagging-strand DNA synthesis and DNA repair. At some sites of repeat expansion, e.g. the myoto...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291863/ https://ncbi.nlm.nih.gov/pubmed/14654691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg920 |
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