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Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients
BACKGROUND: Familial adenomatous polyposis, an autosomal dominant inherited disease caused by germline mutations within the APC gene, is characterized by early onset colorectal cancer as a consequence of the intrinsic phenotypic feature of multiple colorectal adenomatic polyps. The genetic investiga...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918579/ https://ncbi.nlm.nih.gov/pubmed/20649969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-389 |
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