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The role of DNA dependent protein kinase in synapsis of DNA ends
DNA dependent protein kinase (DNA-PK) plays a central role in the non-homologous end-joining pathway of DNA double strand break repair. Its catalytic subunit (DNA-PK(CS)) functions as a serine/threonine protein kinase. We show that DNA-PK forms a stable complex at DNA termini that blocks the action...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291856/ https://ncbi.nlm.nih.gov/pubmed/14654699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg889 |
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