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Is BDNF sufficient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization?

Peripheral nerve injury activates spinal microglia. This leads to enduring changes in the properties of dorsal horn neurons that initiate central sensitization and the onset of neuropathic pain. Although a variety of neuropeptides, cytokines, chemokines and neurotransmitters have been implicated at...

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Detalhes bibliográficos
Main Authors: Biggs, James E, Lu, Van B, Stebbing, Martin J, Balasubramanyan, Sridhar, Smith, Peter A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918544/
https://ncbi.nlm.nih.gov/pubmed/20653959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-44
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