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Gabapentin prevents oxaliplatin-induced central sensitization in the dorsal horn neurons in rats

OBJECTIVE(S): The present study aims to study the alteration of glutamatergic transmission in the dorsal horn neurons and the effect of gabapentin on oxaliplatin-induced neuropathic pain in rats. MATERIALS AND METHODS: Oxaliplatin (5 mg/kg) or saline was administered to adult male Sprague-Dawley rat...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Ruyang, Teng, Yang, Zhao, Wei, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475658/
https://ncbi.nlm.nih.gov/pubmed/26124936
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