Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication

Large T antigen is the replicative helicase of simian virus 40. Its specific binding to the origin of replication and oligomerization into a double hexamer distorts and unwinds dsDNA. In viral replication, T antigen acts as a functional homolog of the eukaryotic minichromosome maintenance factor MCM...

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Vydáno v:EMBO J
Hlavní autoři: Gomez-Lorenzo, Maria G., Valle, Mikel, Frank, Joachim, Gruss, Claudia, Sorzano, Carlos Oscar S., Chen, Xiaojiang S., Donate, Luis Enrique, Carazo, Jose Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
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Articles
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14633980/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg612
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