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Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes
‘Radical SAM’ enzymes generate catalytic radicals by combining a 4Fe–4S cluster and S-adenosylmethionine (SAM) in close proximity. We present the first crystal structure of a Radical SAM enzyme, that of HemN, the Escherichia coli oxygen-independent coproporphyrinogen III oxidase, at 2.07 Å resolutio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291839/ https://ncbi.nlm.nih.gov/pubmed/14633981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg598 |
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