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Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein

Autoimmunity is a surprisingly common complication of primary immunodeficiencies, yet the molecular mechanisms underlying this clinical observation are not well understood. One widely known example is provided by Wiskott-Aldrich syndrome (WAS), an X-linked primary immunodeficiency disorder caused by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nikolov, Nikolay P., Shimizu, Masaki, Cleland, Sophia, Bailey, Daniel, Aoki, Joseph, Strom, Ted, Schwartzberg, Pamela L., Candotti, Fabio, Siegel, Richard M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918330/
https://ncbi.nlm.nih.gov/pubmed/20457871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-237560
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