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Inhibition of hemagglutination activity of influenza A viruses by SP-A1 and SP-A2 variants expressed in CHO cells

Surfactant protein A (SP-A) inhibits hemagglutination (HA) activity and infectivity of Influenza A viruses (IAV). As we have showed before in different assays, SP-A2 gene products are more active than SP-A1. Here, we hypothesized that SP-A1 and SP-A2 mammalian CHO-cell-expressed proteins also differ...

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Detalhes bibliográficos
Main Authors: Mikerov, Anatoly N., White, Mitch, Hartshorn, Kevan, Wang, Guirong, Floros, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917902/
https://ncbi.nlm.nih.gov/pubmed/17520282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00430-007-0051-4
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