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Effect of Cys(85) on biochemical properties and biological function of human SP-A variants

Four “core” amino acid differences within the collagen-like domain distinguish the human surfactant proteins A1 (SP-A1) variants from the SP-A2 variants. One of these, cysteine 85 that could form intermolecular disulfide bonds, is present in SP-A1 (Cys(85)) and absent in SP-A2 (Arg(85)). We hypothes...

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Autori principali: Wang, Guirong, Myers, Catherine, Mikerov, Anatoly, Floros, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531219/
https://ncbi.nlm.nih.gov/pubmed/17580966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7004569
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