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Interactive Design Strategy for a Multi-Functional PAMAM Dendrimer-Based Nano-Therapeutic Using Computational Models and Experimental Analysis

Molecular dynamics simulations of nano-therapeutics as a final product and of all intermediates in the process of generating a multi-functional nano-therapeutic based on a poly(amidoamine) (PAMAM) dendrimer were performed along with chemical analyses of each of them. The actual structures of the den...

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Detalhes bibliográficos
Main Authors: Lee, Inhan, Majoros, Istvan J., Williams, Christopher R., Athey, Brian D., Baker, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917823/
https://ncbi.nlm.nih.gov/pubmed/20700476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/jctn.2009.1006
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