Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Five resveratrol sulfate metabolites were synthesized and assessed for activities known to be mediated by resveratrol: inhibition of tumor necrosis factor (TNF)-α-induced NFκB activity, cylcooxygenases (COX-1 and COX-2), aromatase, nitric oxide production in endotoxin-stimulated macrophages, and pro...

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Bibliografiske detaljer
Main Authors: Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P., Marler, Laura, Pezzuto, John M., van Breemen, Richard B., Mo, Shunyan, Li, Yongchao, Cushman, Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917805/
https://ncbi.nlm.nih.gov/pubmed/20527891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100274c
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