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Two Purified Domains of Telomerase Reverse Transcriptase Reconstitute Sequence-specific Interactions with RNA

Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) function together to create a uniquely specialized polymerase. Here we have described for the first time domains of bacterially expressed Tetrahymena TERT that interacted directly with TER in the absence of assembly chaperones. We used...

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Bibliographic Details
Main Authors: O’Connor, Catherine M., Lai, Cary K., Collins, Kathleen
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917599/
https://ncbi.nlm.nih.gov/pubmed/15731105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M501211200
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