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Secondary Immunologic Consequences in Chromosome 22q11.2 Deletion Syndrome (DiGeorge Syndrome/Velocardiofacial Syndrome)

Clinical evidence suggests that patients with Chromosome 22q11.2 deletion (Ch22q11.2D) have an increased prevalence of atopic and autoimmune disease and this has been without explanation. We hypothesized that the increase in atopy was due to homeostatic proliferation of T cells leading to a Th2 skew...

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Detalhes bibliográficos
Main Authors: Zemble, R., Prak, E. Luning, McDonald, K., McDonald-McGinn, D., Zackai, E., Sullivan, K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917481/
https://ncbi.nlm.nih.gov/pubmed/20472505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.04.011
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