Pediatric Phase I Trial and Pharmacokinetic Study of Vorinostat: A Children's Oncology Group Phase I Consortium Report

PURPOSE: The purpose of this study was to determine the maximum-tolerated dose (MTD), dose-limiting toxicities (DLT), and pharmacokinetics of vorinostat administered as a single agent and in combination 13-cis retinoic acid (13cRA) in children with refractory solid tumors; to evaluate the tolerabili...

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Bibliografische gegevens
Hoofdauteurs: Fouladi, Maryam, Park, Julie R., Stewart, Clinton F., Gilbertson, Richard J., Schaiquevich, Paula, Sun, Junfeng, Reid, Joel M., Ames, Matthew M., Speights, Roseanne, Ingle, Ashish M., Zwiebel, James, Blaney, Susan M., Adamson, Peter C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Clinical Oncology 2010
Onderwerpen:
Original Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917318/
https://ncbi.nlm.nih.gov/pubmed/20606092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.9119
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