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Crystallization of BMP receptor type IA bound to the antibody Fab fragment AbD1556

An antibody Fab fragment, AbD1556, was selected against the extracellular domain of BMP receptor type IA, which blocks the binding of BMP-2 to BMPR-IA and thereby neutralizes BMP-2 activity. To study the mechanism by which BMPR-IA is recognized and bound by the Fab fragment, the complex of AbD1556 b...

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Détails bibliographiques
Auteurs principaux: Harth, Stefan, Kotzsch, Alexander, Sebald, Walter, Mueller, Thomas Dieter
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917305/
https://ncbi.nlm.nih.gov/pubmed/20693682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110024681
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