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Crystallization of BMP receptor type IA bound to the antibody Fab fragment AbD1556

An antibody Fab fragment, AbD1556, was selected against the extracellular domain of BMP receptor type IA, which blocks the binding of BMP-2 to BMPR-IA and thereby neutralizes BMP-2 activity. To study the mechanism by which BMPR-IA is recognized and bound by the Fab fragment, the complex of AbD1556 b...

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Detalhes bibliográficos
Main Authors: Harth, Stefan, Kotzsch, Alexander, Sebald, Walter, Mueller, Thomas Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917305/
https://ncbi.nlm.nih.gov/pubmed/20693682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110024681
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