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Crystallization of BMP receptor type IA bound to the antibody Fab fragment AbD1556
An antibody Fab fragment, AbD1556, was selected against the extracellular domain of BMP receptor type IA, which blocks the binding of BMP-2 to BMPR-IA and thereby neutralizes BMP-2 activity. To study the mechanism by which BMPR-IA is recognized and bound by the Fab fragment, the complex of AbD1556 b...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917305/ https://ncbi.nlm.nih.gov/pubmed/20693682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110024681 |
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