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Promoting crystallization of antibody–antigen complexes via microseed matrix screening
The application of microseed matrix screening to the crystallization of antibody–antigen complexes is described for a set of antibodies that include mouse anti-IL-13 antibody C836, its humanized version H2L6 and an affinity-matured variant of H2L6, M1295. The Fab fragments of these antibodies were c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917276/ https://ncbi.nlm.nih.gov/pubmed/20693692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444910026041 |
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