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Changes in bone micro-architecture and biomechanical properties in the th3 thalassemia mouse are associated with decreased bone turnover and occur during the period of bone accrual

Osteoporosis and fractures occur frequently in patients with beta thalassemias, a group of congenital hemolytic anemias characterized by decreased synthesis of the beta chain of hemoglobin. In this study, we determined the bone abnormalities of the th3 thalassemia mouse, generated by deletion of the...

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Bibliographische Detailangaben
Hauptverfasser: Vogiatzi, Maria G., Tsay, Jaime, Verdelis, Kostas, Rivella, Stefano, Grady, Robert W, Doty, Stephen, Giardina, Patricia J, Boskey, Adele L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917203/
https://ncbi.nlm.nih.gov/pubmed/20449578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-010-9365-0
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