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A palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres

The catalytic enantioselective synthesis of densely functionalised organic molecules containing all-carbon quaternary stereocentres is a challenge to modern chemical methodology research. The catalytically controlled asymmetric α-alkylation of ketones represents another difficult task and has been o...

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Autors principals: Streuff, Jan, White, David E., Virgil, Scott C., Stoltz, Brian M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917108/
https://ncbi.nlm.nih.gov/pubmed/20697457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.518
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