Vorinostat in Advanced Prostate Cancer Patients Progressing on Prior Chemotherapy (NCI Trial # 6862): Trial results and IL-6 analysis. A study by the DOD Prostate Cancer Clinical Trial Consortium and University of Chicago Phase II Consortium

PURPOSE: This phase II trial was designed to evaluate the efficacy of vorinostat in chemotherapy pretreated patients with metastatic castrate resistant prostate cancer. PATIENTS AND METHODS: Patients with disease progression on one prior chemotherapy, a PSA ≥ 5ng/ml, and adequate organ function were...

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Main Authors: Bradley, Deborah, Rathkopf, Dana, Dunn, Rodney, Stadler, Walter M., Liu, Glenn, Smith, David C., Pili, Roberto, Zwiebel, James, Scher, Howard, Hussain, Maha
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917101/
https://ncbi.nlm.nih.gov/pubmed/19711464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24597
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