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Glycinergic and GABAergic tonic inhibition fine tune inhibitory control in regionally distinct subpopulations of dorsal horn neurons

Inhibition mediated by glycine and GABA in the spinal cord dorsal horn is essential for controlling sensitivity to painful stimuli. Loss of inhibition results in hyperalgesia, a sensitized response to a painful stimulus, and allodynia, a pain-like response to an innocuous stimulus like touch. The la...

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Hlavní autoři: Takazawa, Tomonori, MacDermott, Amy B
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916989/
https://ncbi.nlm.nih.gov/pubmed/20498232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188292
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