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Glycinergic and GABAergic tonic inhibition fine tune inhibitory control in regionally distinct subpopulations of dorsal horn neurons

Inhibition mediated by glycine and GABA in the spinal cord dorsal horn is essential for controlling sensitivity to painful stimuli. Loss of inhibition results in hyperalgesia, a sensitized response to a painful stimulus, and allodynia, a pain-like response to an innocuous stimulus like touch. The la...

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Main Authors: Takazawa, Tomonori, MacDermott, Amy B
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916989/
https://ncbi.nlm.nih.gov/pubmed/20498232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188292
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