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Analyzing protein structure and function using ancestral gene reconstruction

Protein families with functionally diverse members can illuminate the structural determinants of protein function and the process by which protein structure and function evolve. To identify the key amino acid changes that differentiate one family member from another, most studies have taken a “horiz...

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Detalhes bibliográficos
Main Authors: Harms, Michael J., Thornton, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916957/
https://ncbi.nlm.nih.gov/pubmed/20413295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.03.005
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