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Analyzing protein structure and function using ancestral gene reconstruction

Protein families with functionally diverse members can illuminate the structural determinants of protein function and the process by which protein structure and function evolve. To identify the key amino acid changes that differentiate one family member from another, most studies have taken a “horiz...

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Bibliographische Detailangaben
Hauptverfasser: Harms, Michael J., Thornton, Joseph W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916957/
https://ncbi.nlm.nih.gov/pubmed/20413295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.03.005
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