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Spliced Leader Trapping Reveals Widespread Alternative Splicing Patterns in the Highly Dynamic Transcriptome of Trypanosoma brucei

Trans-splicing of leader sequences onto the 5′ends of mRNAs is a widespread phenomenon in protozoa, nematodes and some chordates. Using parallel sequencing we have developed a method to simultaneously map 5′splice sites and analyze the corresponding gene expression profile, that we term spliced lead...

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Hlavní autoři: Nilsson, Daniel, Gunasekera, Kapila, Mani, Jan, Osteras, Magne, Farinelli, Laurent, Baerlocher, Loic, Roditi, Isabel, Ochsenreiter, Torsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916883/
https://ncbi.nlm.nih.gov/pubmed/20700444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001037
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