Trypanosoma brucei RRM1 Is a Nuclear RNA-Binding Protein and Modulator of Chromatin Structure

TbRRM1 of Trypanosoma brucei is a nucleoprotein that was previously identified in a search for splicing factors in T. brucei. We show that TbRRM1 associates with mRNAs and with the auxiliary splicing factor polypyrimidine tract-binding protein 2, but not with components of the core spliceosome. TbRR...

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Gepubliceerd in:mBio
Hoofdauteurs: Naguleswaran, Arunasalam, Gunasekera, Kapila, Schimanski, Bernd, Heller, Manfred, Hemphill, Andrew, Ochsenreiter, Torsten, Roditi, Isabel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Microbiology 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453557/
https://ncbi.nlm.nih.gov/pubmed/25784696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00114-15
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