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MULTIPLE RETINOIC ACID RESPONSE ELEMENTS COOPERATE TO ENHANCE THE INDUCIBILITY OF CYP26A1 GENE EXPRESSION IN LIVER
CYP26A1, which catalyzes the oxidation of all-trans (at)-retinoic acid (RA), is induced moderately by RA in numerous tissues, but is highly responsive in liver. To understand this difference, we have examined the CYP26A1 gene sequence, identified multiple RA response elements (RAREs) and tested them...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916872/ https://ncbi.nlm.nih.gov/pubmed/20682464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2010.05.004 |
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